Listen to this article now

The healthcare industry is under constant change and innovation. With the continuous advancements in medical technology, there is a growing demand for more efficient and effective treatments. This has given rise to many new startups in the healthcare industry that are providing cutting-edge solutions to various problems. Here are 10 of the most promising medical and healthcare startup companies in the USA to look out for in 2022:

1. Path

Path is a mental health company that provides information and resources to help people understand and manage their mental health by connecting with providers through their virtual platform.

The company has raised over $100 million in funding and is quickly expanding its reach. Path is one of the medical and healthcare companies to watch out for in 2022.

2. Wellframe

Wellframe is a digital health company that is developing a platform to strengthen and expand healthcare management. The company was founded in 2011 and it is headquartered in Boston, Massachusetts. Wellframe has raised over $45 million in funding from investors.


The company’s goal is to empower health plans to better advocate for patient needs by utilizing a seamless digital experience. Wellframe has the potential to revolutionize healthcare relationships, and it is definitely a company to watch in the coming years.

3. Cue Health

Cue Health is a medical and healthcare company that is definitely one to look out for in 2022. Founded in 2010, Cue is a health diagnostic startup that offers portable diagnostic testing for Covid-19.

The company’s flagship product is the Cue Diagnostic Kit, a portable device that can be used to test for a variety of conditions in just minutes.  By offering a convenient and affordable way to diagnostic testing, Cue is making it easier for both individuals and healthcare professionals to get reliable results in minutes.

4. Flatiron Health

Flatiron Health is one of the most promising healthcare companies to watch out for in 2022. Flatiron Health is a healthcare technology company that provides oncology-specific electronic health records, analytics software, and clinical decision support tools. The company was founded in 2012 by Nat Turner and Zach Weinberg.


In 2018, Flatiron Health was acquired by pharmaceutical giant, Roche, for $1.9 billion. Their cutting-edge technology is revolutionizing the way cancer is treated and research is conducted. With the backing of a major pharmaceutical company like Roche, Flatiron Health is poised to make significant advances in the field of cancer care.

5. Modern Fertility

Modern Fertility is a healthcare company that provides fertility testing and resources for women. The company was founded in 2017 by Afton Vechery and Carly Leahy. Modern Fertility is headquartered in San Francisco, California. In 2018, Modern Fertility raised $15 million in Series A funding led by Forerunner Ventures.

Modern Fertility is one of the leading companies in the fertility space and is poised for continued growth in the coming years. Modern Fertility has a clear mission to empower women with knowledge about their fertility and provide them with the resources they need to make informed decisions about their reproductive health.

6. Hinge Health

Hinge Health is a healthcare company seeking to deliver in-home physical therapy services. The company uses wearable body tracking devices and virtual communication with healthcare professionals to provide its services. Hinge recently concluded a $300 million funding round, which valued the company at $3 billion. The new funding will be used to expand the company’s operations and continue its mission of providing accessible, affordable, and effective musculoskeletal care.


7. Headspace Inc.

Headspace Inc. is a healthcare company that specializes in providing mental health services. The company was founded in 2010 by Andy Puddicombe and Richard Pierson, and it has since grown to become one of the leading providers of mental health services in the world.

Headspace offers a wide range of services, including meditation and mindfulness training, app-based therapy, and in-person counseling. The company has been incredibly successful, expanding rapidly and raising over $100 million in funding with future growth expected.

8. Devoted Health

Devoted Health is on a mission to provide seniors with the best possible care and make the healthcare system work better for everyone. Founded in 2017 by Todd and Ed Park, Devoted Health is a Medicare Advantage plan that offers seniors an alternative to traditional Medicare. With $2B in funding, the company plans to use its technology and data to improve the quality of care for seniors.

9. Natalist

Natalist is a healthcare company that is focused on helping women who want to have children. They offer a variety of services, including fertility testing, genetic counseling, and IVF.


Natalist has a team of experienced reproductive endocrinologists, obstetricians, and urologists who are dedicated to helping women have healthy pregnancies. In addition, Natalist offers funding for IVF and other fertility treatments. Natalist is a great choice for women who are looking for comprehensive fertility care.

10. Tempus

Tempus is a medical technology company that uses artificial intelligence to analyze patient data and improve healthcare treatments. The goal of Tempus is to help doctors make better decisions about patient care. The company was founded in 2015 by Eric Lefkofsky, who is also the co-founder of Groupon. Tempus has raised over $1 billion in funding from investors such as New Enterprise Associates and Revolution Growth.


These are some of the top medical/healthcare startup companies in the USA to keep an eye on for potential investment opportunities or job openings in 2022. These companies are on the cutting edge of medical technology and leadership within their field which positions them well for continued success in the coming years.